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Penile Cancer – Symptoms, Diagnosis & Treatment | I D Cancer Center

What Is Penile Cancer?

Penile cancer is a rare malignancy that develops in the skin or tissues of the penis.
Most cases start in the squamous cells on the foreskin or glans (tip of the penis).

Early diagnosis greatly improves treatment success and long-term outcomes.


⭐ Who Is at Risk?

Risk factors for penile cancer include:

  • HPV infection (Human Papillomavirus)

  • Poor genital hygiene

  • Phimosis (tight foreskin)

  • Smoking and tobacco use

  • Age > 50 years

  • Chronic inflammation or infections

  • Multiple sexual partners

  • Weakened immune system


⭐ Signs & Symptoms

Penile cancer often begins subtly. Seek medical evaluation if you notice:

  • Painless lump, sore, or ulcer on the penis

  • Redness, thickening, or skin changes

  • Foul-smelling discharge

  • Bleeding or persistent rash

  • Wart-like growth

  • Non-healing ulcer (most important)

  • Swelling of lymph nodes in the groin

Any symptom persisting more than 2 weeks requires medical assessment.


⭐ How Penile Cancer Is Diagnosed

At I D Cancer Center, diagnosis follows an evidence-based, structured protocol:

✔ Clinical Examination

Assessment of lesions, foreskin mobility, and lymph nodes.

✔ Biopsy (Gold Standard)

A small tissue sample confirms cancer type.

✔ Imaging Tests

  • Ultrasound

  • MRI of penis

  • CT scan (for spread)

  • PET-CT when required

✔ Lymph Node Assessment

Detecting spread to groin nodes is critical for staging.


⭐ Staging (Clinical Stages)

  • Stage I: Cancer limited to superficial layers

  • Stage II: Invasion into deeper tissues

  • Stage III: Spread to groin lymph nodes

  • Stage IV: Distant spread

Early-stage tumors are highly curable.


⭐ Treatment Options at I D Cancer Center

Management depends on tumor size, spread, and patient preference.

1. Organ-Preserving Treatments

For early disease:

  • Topical chemotherapy/Imiquimod

  • Laser therapy

  • Wide local excision

  • Circumcision (if foreskin is involved)

  • Mohs microsurgery

2. Surgery

  • Partial penectomy – removes tumor while preserving function

  • Total penectomy – for large or advanced tumors

  • Inguinal lymph node removal when nodes are affected

3. Radiation Therapy

At I D Cancer Center, we use precision technologies to preserve organ function:

  • IMRT

  • VMAT/Arc Therapy

  • Brachytherapy (in select cases)

Radiation can be curative for early tumors or used after surgery to reduce recurrence.

4. Chemotherapy

Used for:

  • Locally advanced disease

  • Lymph node involvement

  • Metastatic cancer

Common drugs include cisplatin-based combinations.

5. Targeted Therapy / Immunotherapy

Considered in selected cases based on tumor biology and HPV association.


⭐ Prognosis

Prognosis depends on:

  • Stage at diagnosis

  • Lymph node involvement

  • Tumor grade

  • Treatment response

Early detection and organ-preserving treatments significantly improve survival and quality of life.


⭐ Prevention

  • Maintain good genital hygiene

  • Circumcision (especially in childhood) reduces risk

  • Avoid tobacco

  • Practice safe sex; reduce risk of HPV infection

  • HPV vaccination for boys (recommended by global guidelines)


⭐ Why Choose I D Cancer Center?

  • Expert evaluation by Dr. Sunil Kumar

  • Advanced radiotherapy techniques (IMRT/VMAT)

  • Multidisciplinary tumor board

  • Organ-preserving treatment options

  • Privacy-focused, compassionate patient care

  • Modern diagnostics and personalized protocols