Fallopian Tube Cancer Treatment | I D Cancer Center Lucknow
Overview
Fallopian Tube Cancer is a rare type of gynecological cancer that starts in the fallopian tubes — the thin ducts connecting the ovaries to the uterus. Although uncommon, it behaves similarly to ovarian cancer and often presents with vague or subtle symptoms, making early diagnosis challenging.
With advances in imaging, pathology, targeted therapy, and precision radiotherapy, outcomes for fallopian tube cancer have significantly improved.
At I D Cancer Center, we provide comprehensive diagnosis, advanced treatment options, and compassionate support for women affected by this rare condition.
Fallopian Tube Cancer is a rare type of gynecological cancer that starts in the fallopian tubes — the thin ducts connecting the ovaries to the uterus. Although uncommon, it behaves similarly to ovarian cancer and often presents with vague or subtle symptoms, making early diagnosis challenging.
With advances in imaging, pathology, targeted therapy, and precision radiotherapy, outcomes for fallopian tube cancer have significantly improved.
At I D Cancer Center, we provide comprehensive diagnosis, advanced treatment options, and compassionate support for women affected by this rare condition.
What Are the Fallopian Tubes?
Fallopian tubes are two narrow structures responsible for transporting eggs from the ovaries to the uterus. Cancer developing in this area most commonly originates from the epithelial lining of the tubes.
Studies now show that many ovarian cancers may actually start in the fallopian tubes.
Fallopian tubes are two narrow structures responsible for transporting eggs from the ovaries to the uterus. Cancer developing in this area most commonly originates from the epithelial lining of the tubes.
Studies now show that many ovarian cancers may actually start in the fallopian tubes.
Types of Fallopian Tube Cancer
1. High-Grade Serous Carcinoma (Most Common)
Aggressive but highly responsive to chemotherapy.
Aggressive but highly responsive to chemotherapy.
2. Endometrioid Carcinoma
Less common and often associated with endometriosis.
Less common and often associated with endometriosis.
3. Transitional Cell Carcinoma
4. Sarcomas
Extremely rare.
Extremely rare.
Causes & Risk Factors
While the exact cause is unknown, certain factors increase risk:
BRCA1/BRCA2 gene mutations
Strong family history of ovarian or breast cancer
Age above 50
Infertility or no pregnancies
Chronic inflammation of reproductive organs
Genetic syndromes (Lynch syndrome)
Protective Factors
Oral contraceptive use
Tubal ligation
Breastfeeding
While the exact cause is unknown, certain factors increase risk:
BRCA1/BRCA2 gene mutations
Strong family history of ovarian or breast cancer
Age above 50
Infertility or no pregnancies
Chronic inflammation of reproductive organs
Genetic syndromes (Lynch syndrome)
Protective Factors
Oral contraceptive use
Tubal ligation
Breastfeeding
Symptoms
Symptoms often mimic ovarian or pelvic conditions:
Symptoms often mimic ovarian or pelvic conditions:
Common Signs
Abnormal vaginal bleeding or spotting
Pelvic or lower abdominal pain
Persistent bloating
Unusual vaginal discharge
Back pain
Feeling of pelvic pressure
Pain during intercourse
Loss of appetite or weight loss
Because symptoms are nonspecific, early evaluation is important.
Abnormal vaginal bleeding or spotting
Pelvic or lower abdominal pain
Persistent bloating
Unusual vaginal discharge
Back pain
Feeling of pelvic pressure
Pain during intercourse
Loss of appetite or weight loss
Because symptoms are nonspecific, early evaluation is important.
Diagnosis at I D Cancer Center
We use a structured, multimodal approach for accurate diagnosis:
We use a structured, multimodal approach for accurate diagnosis:
1. Clinical Evaluation
Pelvic examination
Symptom assessment
Pelvic examination
Symptom assessment
2. Imaging
Ultrasound (Transvaginal / Pelvic)
CT Scan / MRI of the abdomen & pelvis
PET-CT for full-body staging
Ultrasound (Transvaginal / Pelvic)
CT Scan / MRI of the abdomen & pelvis
PET-CT for full-body staging
3. Tumor Markers
CA-125
HE4 (selected cases)
CA-125
HE4 (selected cases)
4. Biopsy / Surgical Evaluation
Laparoscopy or laparotomy
Pathology with immunohistochemistry
Genetic testing if BRCA mutation suspected
Laparoscopy or laparotomy
Pathology with immunohistochemistry
Genetic testing if BRCA mutation suspected
5. Staging
Based on FIGO guidelines for gynecological cancers.
Based on FIGO guidelines for gynecological cancers.
Treatment Options
Treatment depends on the stage, spread, and overall health.
Treatment depends on the stage, spread, and overall health.
⭐ 1. Surgery (Primary Treatment)
Performed at specialist gynecology-oncology centers; postoperative care coordinated at I D Cancer Center.
Typical surgical procedures include:
Total hysterectomy
Bilateral salpingo-oophorectomy
Omentectomy
Pelvic and para-aortic lymph node sampling
Removal of visible tumor deposits (cytoreduction)
Performed at specialist gynecology-oncology centers; postoperative care coordinated at I D Cancer Center.
Typical surgical procedures include:
Total hysterectomy
Bilateral salpingo-oophorectomy
Omentectomy
Pelvic and para-aortic lymph node sampling
Removal of visible tumor deposits (cytoreduction)
⭐ 2. Chemotherapy
Fallopian tube cancer responds well to platinum-based chemotherapy.
Common regimen:
Carboplatin + Paclitaxel
Given in 3–6 cycles depending on stage.
Fallopian tube cancer responds well to platinum-based chemotherapy.
Common regimen:
Carboplatin + Paclitaxel
Given in 3–6 cycles depending on stage.
⭐ 3. Targeted Therapy
Used to improve survival and reduce recurrence:
PARP inhibitors (Olaparib, Niraparib) — especially for BRCA-positive patients
Bevacizumab (angiogenesis inhibitor)
Used to improve survival and reduce recurrence:
PARP inhibitors (Olaparib, Niraparib) — especially for BRCA-positive patients
Bevacizumab (angiogenesis inhibitor)
⭐ 4. Radiation Therapy
Radiotherapy plays a role in selected cases:
At I D Cancer Center, therapy is delivered with:
IMRT
IGRT
VMAT
Used for:
Persistent pelvic disease
Recurrence
Symptom relief
Radiotherapy plays a role in selected cases:
At I D Cancer Center, therapy is delivered with:
IMRT
IGRT
VMAT
Used for:
Persistent pelvic disease
Recurrence
Symptom relief
⭐ 5. Immunotherapy (Selected Cases)
For recurrent or resistant cancers:
Pembrolizumab
Dostarlimab (depending on molecular profile)
For recurrent or resistant cancers:
Pembrolizumab
Dostarlimab (depending on molecular profile)
Follow-Up Care
Regular follow-up is essential for monitoring recurrence and managing long-term health.
Schedule includes:
Physical and pelvic exams
CA-125 monitoring
Imaging studies as needed
Symptom & quality-of-life evaluation
Regular follow-up is essential for monitoring recurrence and managing long-term health.
Schedule includes:
Physical and pelvic exams
CA-125 monitoring
Imaging studies as needed
Symptom & quality-of-life evaluation
Fertility & Emotional Support
For younger women, we offer:
Fertility counselling
Fertility-preserving options (selected early cases)
Psychological and emotional support
Nutritional guidance
For younger women, we offer:
Fertility counselling
Fertility-preserving options (selected early cases)
Psychological and emotional support
Nutritional guidance
Prognosis
Early-stage fallopian tube cancer has a good prognosis. Advanced-stage cancers can also respond well to combined chemotherapy and targeted therapy.
Early-stage fallopian tube cancer has a good prognosis. Advanced-stage cancers can also respond well to combined chemotherapy and targeted therapy.
