Childhood Brain Tumor Treatment | I D Cancer Center Lucknow
Expert Evaluation & Advanced Pediatric Neuro-Oncology Care at I D Cancer Center, Lucknow
Childhood brain tumors are among the most common solid tumors in children. They can affect different parts of the brain or spinal cord and may impact how a child sees, walks, learns, or interacts. Early diagnosis and timely treatment play a crucial role in achieving the best outcomes.
What Are Childhood Brain Tumors?
Childhood brain tumors occur when abnormal cells grow uncontrollably in the brain or spinal cord. These tumors may be:
Benign (non-cancerous)
Malignant (cancerous)
Low-grade (slow-growing)
High-grade (fast-growing)
Common types include:
Medulloblastoma
Low-grade glioma
High-grade glioma
Ependymoma
Pontine glioma / DIPG
Craniopharyngioma
Germinoma and other germ cell tumors
Each tumor behaves differently and requires tailored care.
Childhood brain tumors occur when abnormal cells grow uncontrollably in the brain or spinal cord. These tumors may be:
Benign (non-cancerous)
Malignant (cancerous)
Low-grade (slow-growing)
High-grade (fast-growing)
Common types include:
Medulloblastoma
Low-grade glioma
High-grade glioma
Ependymoma
Pontine glioma / DIPG
Craniopharyngioma
Germinoma and other germ cell tumors
Each tumor behaves differently and requires tailored care.
Common Symptoms of Childhood Brain Tumors
Symptoms depend on the tumor’s location and size. Watch for:
Persistent headache (especially in the morning)
Repeated vomiting without fever
Vision changes or double vision
Difficulty walking or balancing
Seizures
Weakness in limbs
Behavioral or personality changes
Poor school performance
Increased sleepiness or irritability
Head enlargement in infants
Early medical evaluation helps prevent complications and improves treatment success.
Symptoms depend on the tumor’s location and size. Watch for:
Persistent headache (especially in the morning)
Repeated vomiting without fever
Vision changes or double vision
Difficulty walking or balancing
Seizures
Weakness in limbs
Behavioral or personality changes
Poor school performance
Increased sleepiness or irritability
Head enlargement in infants
Early medical evaluation helps prevent complications and improves treatment success.
How Childhood Brain Tumors Are Diagnosed
I D Cancer Center follows a detailed, child-friendly diagnostic approach:
I D Cancer Center follows a detailed, child-friendly diagnostic approach:
1. Neurological Examination
Checks coordination, reflexes, balance, and vision.
Checks coordination, reflexes, balance, and vision.
2. Brain Imaging
MRI brain with contrast (gold standard)
MRI spine (if tumor likely to spread)
CT scan (in emergency cases)
MRI brain with contrast (gold standard)
MRI spine (if tumor likely to spread)
CT scan (in emergency cases)
3. Tissue Diagnosis
Surgical biopsy
Excisional surgery (removal of tumor when possible)
Surgical biopsy
Excisional surgery (removal of tumor when possible)
4. Pathology & Molecular Testing
Tumor subtype identification
Genetic mutations (BRAF, H3K27M, MGMT, IDH, etc.)
Helps guide modern targeted therapy
Tumor subtype identification
Genetic mutations (BRAF, H3K27M, MGMT, IDH, etc.)
Helps guide modern targeted therapy
5. Additional Tests
Blood tests
Hormone panel (pituitary/hypothalamic tumors)
Lumbar puncture (in selected tumors like medulloblastoma)
Blood tests
Hormone panel (pituitary/hypothalamic tumors)
Lumbar puncture (in selected tumors like medulloblastoma)
Treatment Options at I D Cancer Center
Treatment depends on age, tumor type, grade, and location. We follow international pediatric neuro-oncology protocols.
Treatment depends on age, tumor type, grade, and location. We follow international pediatric neuro-oncology protocols.
1. Neurosurgery
Goals include:
Maximum safe removal
Biopsy for diagnosis
- Relieving pressure in the brainPerformed by expert neurosurgeon partners.
2. Radiation Therapy
Modern pediatric-safe technologies at I D Cancer Center include:
IMRT / VMAT precision radiotherapy
IGRT for daily accuracy
SRS/SBRT for small or residual tumors
Craniospinal irradiation (CSI) — for medulloblastoma and germ cell tumors
Brainstem-safe and optic-nerve-sparing plans
We prioritize normal tissue protection to minimise long-term side effects.
Modern pediatric-safe technologies at I D Cancer Center include:
IMRT / VMAT precision radiotherapy
IGRT for daily accuracy
SRS/SBRT for small or residual tumors
Craniospinal irradiation (CSI) — for medulloblastoma and germ cell tumors
Brainstem-safe and optic-nerve-sparing plans
We prioritize normal tissue protection to minimise long-term side effects.
3. Chemotherapy
Used for many pediatric brain tumors, especially:
Medulloblastoma
Ependymoma
High-grade gliomas
Germ cell tumors
Tumors where radiation must be delayed (very young children)
Used for many pediatric brain tumors, especially:
Medulloblastoma
Ependymoma
High-grade gliomas
Germ cell tumors
Tumors where radiation must be delayed (very young children)
4. Targeted Therapy & Immunotherapy
Based on tumor genetics:
BRAF inhibitors
MEK inhibitors
Immunotherapy in clinical-appropriate cases
Based on tumor genetics:
BRAF inhibitors
MEK inhibitors
Immunotherapy in clinical-appropriate cases
5. Supportive & Rehabilitation Care
Physiotherapy
Speech & occupational therapy
Eye and hearing evaluations
Hormonal support
Psychological counselling
Physiotherapy
Speech & occupational therapy
Eye and hearing evaluations
Hormonal support
Psychological counselling
6. Long-term Follow-up
Essential for:
Monitoring tumor control
Growth & development
Learning abilities
Emotional well-being
Essential for:
Monitoring tumor control
Growth & development
Learning abilities
Emotional well-being
Prognosis
Prognosis varies based on tumor type and stage, but outcomes have improved significantly due to:
Advanced neurosurgery
Molecular-guided therapy
Highly precise radiotherapy
Comprehensive rehabilitation services
Many children go on to lead healthy, fulfilling lives with the right treatment and follow-up.
Prognosis varies based on tumor type and stage, but outcomes have improved significantly due to:
Advanced neurosurgery
Molecular-guided therapy
Highly precise radiotherapy
Comprehensive rehabilitation services
Many children go on to lead healthy, fulfilling lives with the right treatment and follow-up.

